Handheld Microflow Cytometer Based on a Motorized Smart Pipette, a Microfluidic Cell Concentrator, and a Miniaturized Fluorescence Microscope

Miniaturizing flow cytometry requires a comprehensive approach to redesigning the conventional fluidic and optical systems to have a small footprint and simple usage and to enable rapid cell analysis.Microfluidic methods have addressed some challenges in limiting the realization of microflow cytometry, but most microfluidics-based flow cytometry te

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Deregulation of Interferon Signaling in Malignant Cells

Interferons (IFNs) are a family of cytokines with potent antiproliferative, antiviral, and immunomodulatory Stocking properties.Much has been learned about IFNs and IFN-activated signaling cascades over the last 50 years.Due to their potent antitumor effects in vitro and in vivo, recombinant IFNs have been used extensively over the years, alone or

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Crystal Structure, Hirshfeld Surface Analysis, In-Silico and Antimycotic Investigations of Methyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2-dihydropyrimidine-5-carboxylate

Herein, we report the preparation of methyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2-dihydropyrimidine-5-carboxylate 2, obtained by the regioselective oxidative dehydrogenation of the dihydropyrimidine derivative 1 in the presence of cerium ammonium nitrate.The structure of compound Tridonic PCA Ballasts 2 was investigated by single-crystal X-ray diffr

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